Creatine, widely recognized for its role in enhancing muscle strength and athletic performance, is increasingly being studied for its potential effects on mental health and digestive wellness. Emerging research suggests that creatine supplementation may influence brain energy metabolism, neurotransmitter balance, and gut microbiota, potentially benefiting individuals with anxiety or digestive concerns. While early studies show promising links between creatine intake and reduced anxiety symptoms, as well as improved gut function, evidence remains limited and context-specific.